Kilder

Kilder:

1) Bryony Close et al., Euthanasia of Experimental Animals: Report Prepared for the European Commission (Luxembourg: Office for Official Publications of the European Communities, 1997): s. 14.

2) Guidelines for the use of cell lines in biomedical research, British Journal of Cancer (201) 111, 1021-1046, doi: 10.1038/bjc.2014.166, http://www.nature. com/bjc/journal/v111/n6/full/bjc2014166a.html 

3) http://www.ema.europa.eu/docs/en_GB/document_library/Other/2009/09/WC500003715.pdf

4) ESAC statement on the use of FCS and other animal-derived supplements 7-8 May. https://eurl-ecvam.jrc.ec.europa.eu/about-ecvam/archive-publications/publication/ESAC28_statement_FCS_20080508.pdf

5) WHO, Recommendations for the evaluation of animal cell cultures as substrates for the manufactore of biological medicinal products and for the characterization of cell banks, 2010

6) Direktiv 2010/63/EU

7 + 8) Gerhard Gstraunthaler et al., A Severe Case of Fraudulent Blending of Fetal Bovine Serum Strengthens the Case for Serum-free Cell and Tissue Culture Applications i: ATLA 42 (2014): s. 207-209.

Se desuden:
 Khodakabus A. & Baar K “The Effect of Serum Origin on Tissue Engineered Skeletal Muscle Function”, Journal of Cellular Biology Vol 115, Issue 12, December 2014, pp. 2198-207,  https://onlinelibrary.wiley.com/doi/abs/10.1002/jcb.24938
 Alyssa Master, Ph.D. “Shifting Quality of FBS may impact your experiments” artikel i GenEngNews https://www.genengnews.com/gen-exclusives/shifting-quality-of-fbs-may-impact-your-experiments/77900873 
The Cell Culture Dish. Om serumfri mediers reproducerbarhed: http://cellculturedish.com/2015/09/achieving-control-and-reproducibility-of-cell-culture-by-eliminating-serum/ 
Om svindel med serum: https://atlasbio.com/wp-content/uploads/2017/07/Determining-biochemical-characteristic-of-Fetal-Bovine-Serum-Final.pdf

 

 

Godcellekultur.dk ønsker at informere om næringsmediet føtalt kalveserum, og hvorfor man som forsker skal erstatte produktet med et kemisk-defineret næringsmedie. Vi håber, at du vil gennemlæse de enkelte afsnit og se, at der findes indlysende både dyreetiske og videnskabelige grunde til at gå bort fra føtalt kalveserum (forkortet FBS – Fetal Bovine Serum eller FCS – Fetal Calf Serum).

Bag GodCellekultur.dk står Landsforeningen Forsøgsdyrenes Værn og Alternativfondet. Begge arbejder for at hjælpe de mest glemte af alle dyr – forsøgsdyrene.
Foreningen og Fondet går sammen om at støtte forskning, der kan erstatte dyreforsøg med andre metoder.